agen·​e·​sis (ˌ)ā-ˈje-nə-səs How to pronounce agenesis (audio)
: lack or failure of development (as of a body part)

Examples of agenesis in a Sentence

Recent Examples on the Web However, the absence of both in utero (bilateral renal agenesis) impacts the development of the lungs. Cara Lynn Shultz, Peoplemag, 27 Oct. 2023 White took a hit during practice that caused abdominal pain, which led to the revelation that he was born with one kidney, a condition called renal agenesis. Chicago Tribune Staff, Chicago Tribune, 12 June 2023 Renal agenesis – the absence of kidneys – was on the list. Elizabeth Cohen, CNN, 2 May 2023 People with this form of agenesis have trouble moving information from one hemisphere to the other. Carl Zimmer, Discover Magazine, 16 May 2011 She was also born with a rare congenital condition called sacral agenesis. James Brown, USA TODAY, 11 Dec. 2022 This rare condition is likely a case of agenesis, the absence or failure of organ development, says Fiona Brockbank, Cats Protection’s senior field veterinary officer, in the blog. Jacquelyne Germain, Smithsonian Magazine, 14 Nov. 2022 Domenech’s brother Colin, who turns 28 on April 30, was born without the band of white matter that connects the two hemispheres in the brain, a condition called agenesis of the corpus callosum. Edward Lee, Baltimore Sun, 16 Apr. 2022 The men had been sharing their own struggles with depression and Cooper Jones, who was born with a rare congenital condition called sacral agenesis, began to feel a moment of connection. Sam Gillette,, 6 Apr. 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'agenesis.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


a- entry 2 + genesis, on the model of French agénésie

First Known Use

circa 1879, in the meaning defined above

Time Traveler
The first known use of agenesis was circa 1879

Dictionary Entries Near agenesis

Cite this Entry

“Agenesis.” Dictionary, Merriam-Webster, Accessed 2 Mar. 2024.

Medical Definition


agen·​e·​sis (ˈ)ā-ˈjen-ə-səs How to pronounce agenesis (audio)
plural ageneses -ˌsēz How to pronounce agenesis (audio)
: lack or failure of development (as of a body part)

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