replication

noun

rep·​li·​ca·​tion ˌre-plə-ˈkā-shən 

1

a

: answer, reply

b(1)

: an answer to a reply : rejoinder

(2)

: a plaintiff's reply to a defendant's plea, answer, or counterclaim

2

: echo, reverberation

3

a

: copy, reproduction

b

: the action or process of reproducing or duplicating

replication of DNA

viral replication

4

: performance of an experiment or procedure more than once

Synonyms

• reproduction
• copy
• replica

Examples of replication in a Sentence

bought a smaller and cheaper replication of the marble statue for his garden

we'll need to do a replication of that experiment so we can collect more data

Recent Examples on the Web

On face value, this seems counterproductive for even a microorganism, where replication and in turn genetic survival is a driving force. —New Atlas, 16 Oct. 2025

In a world of infinite replication, the rarest thing left will be something — or someone — real. —Big Think, 16 Oct. 2025

The mechanisms that enable replication—the model weights themselves, the precise optimization subroutines, the engineering tricks that enhance model capabilities—deserve tight custody. —MSNBC Newsweek, 8 Oct. 2025

Mutations are copying errors that occur naturally during the replication process. —Deborah Fuller, CNN Money, 10 Sep. 2025

Word History

Etymology

Middle English replicacioun "answer, rejoinder, argument, repetition," borrowed from Anglo-French & Late Latin; Anglo-French replicacion "answer to an argument or statement of an opponent," borrowed from Late Latin replicātiōn-, replicātiō "act of bending or folding, repetition, reply, replication in court," going back to Latin, "contrary rotation, replication," from replicāre "to turn back on itself, bend back, go over (a thought, topic) repeatedly, make a replication" (Late Latin also "to restore, repeat, reply") + -tiōn-, -tiō, suffix of verbal action — more at replicate entry 1

First Known Use

14th century, in the meaning defined at sense 1a

Rhymes for replication

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

replication

noun

rep·​li·​ca·​tion ˌrep-lə-ˈkā-shən 

1

: very exact copying or duplication

2

: an act or process of copying or duplication

Medical Definition

replication

noun

rep·​li·​ca·​tion ˌrep-lə-ˈkā-shən 

1

: the action or process of reproducing or duplicating

replication of DNA

2

: performance of an experiment or procedure more than once

Legal Definition

replication

noun

rep·​li·​ca·​tion ˌre-plə-ˈkā-shən 

: reply

Etymology

Anglo-French, from Middle French, from Late Latin replicatio, from Latin, action of folding back, from replicare to fold back