RNAi

noun

ˌär-ˌen-ˌā-ˈī 

: rna interference

Examples of RNAi in a Sentence

Recent Examples on the Web

Arrowhead’s RNAi drugs cut fat in early studies Arrowhead Pharmaceuticals said this morning that its gene-silencing candidates helped people with obesity lose fat. — Elaine Chen, STAT, 6 Jan. 2026

Based on a mechanism called RNA interference (RNAi), the spray targets a vital gene in the Colorado potato beetle. — Byerik Stokstad, science.org, 27 June 2024

Investors are closely watching Intellia’s program in ATTR-CM after Alnylam reported positive data on its RNAi treatment earlier this week. — Elaine Chen, STAT, 26 June 2024

Alnylam is a pioneer in a drug technology called RNA interference, or RNAi, that silences genes that play a role in disease. — Joseph Walker, WSJ, 3 Aug. 2022

Arrowhead Pharmaceuticals’ therapies trigger the RNAi mechanism in cells to reduce the amount of a target protein produced. — Ricardo Torres, Milwaukee Journal Sentinel, 9 May 2022

The company also entered into an agreement with PeptiDream to develop peptide-small interfering RNA (siRNA) conjugates aimed to deliver RNAi therapeutics to tissues outside the liver. — Trefis Team, Forbes, 1 Nov. 2021

Daryl Gohl, group leader of the University of Minnesota Genomics Center Innovation Lab, was among the researchers who sequenced the genome of the zebra mussel, published in 2019, and is now working on the RNAi project. — Morgan Greene, chicagotribune.com, 30 July 2021

Word History

First Known Use

1998, in the meaning defined above

Medical Definition

RNAi

noun

ˌär-ˌen-ˌā-ˈī

: rna interference