Parkinson's disease

noun

Par·​kin·​son's disease ˈpär-kən-sənz- 

variants or less commonly Parkinson disease or Parkinson's or Parkinson's syndrome

: a chronic progressive neurological disease chiefly of later life that is linked to decreased dopamine production in the substantia nigra and is marked especially by tremor of resting muscles, rigidity, slowness of movement, impaired balance, and a shuffling gait

called also paralysis agitans

Examples of Parkinson's disease in a Sentence

Recent Examples on the Web

There are two forms of Lewy body dementia: Dementia with Lewy bodies (DLB) and Parkinson's disease dementia. —Anthony Robledo, USA Today, 12 July 2025

They're also used to relieve muscle stiffness in Parkinson's disease sufferers and even as a common sleep aid. —New Atlas, 11 July 2025

The singer was later diagnosed with Parkinson's disease in 2019. —Rachel Raposas, People.com, 10 July 2025

The event came after Osbourne stepped back from live performances due health issues including Parkinson's disease. —Shania Russell, EW.com, 7 July 2025

Word History

Etymology

James Parkinson †1824 English physician

First Known Use

1877, in the meaning defined above

Rhymes for Parkinson's disease

• ferromanganese
• mephistopheles
• ostracods
• abcs
• absentees
• addressees
• adoptees
• allottees
• amputees
• antifreeze
• appellees
• appointees

Kids Definition

Parkinson's disease

noun

Par·​kin·​son's disease ˈpär-kən-sənz- 

: a disease chiefly of later life that tends to get steadily worse and is marked especially by stiff and trembling muscles, slowness of movement, and a shuffling way of walking

Medical Definition

Parkinson's disease

noun

Par·​kin·​son's disease ˈpär-kən-sənz- 

variants also Parkinson disease

-sən-

or Parkinson's

: a chronic progressive neurological disease chiefly of later life that is linked to decreased dopamine production in the substantia nigra, is of unknown cause, and is marked especially by tremor of resting muscles, rigidity, slowness of movement, impaired balance, and a shuffling gait

called also paralysis agitans, parkinsonian syndrome, parkinsonism, Parkinson's syndrome