multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

When Ashley Eklin received a diagnosis of multiple sclerosis in 2022, her outlook on life changed forever. — Scott Neuman, NPR, 24 July 2026

Maybe even traumatic brain injuries and multiple sclerosis, too. — Tom Bartlett, The Atlantic, 24 July 2026

This is why he’s partnered with biotechnology company Genentech as part of their Hidden GeMS campaign, which features the many varied stories of individuals living with multiple sclerosis. — Tabitha Parent, PEOPLE, 15 July 2026

Similarly, Sanofi’s tolebrutinib for non-relapsing secondary progressive multiple sclerosis, and Aldeyra Therapeutics’ reproxalap for ocular disease have each generated substantial concern among patients, clinicians, sponsors, or advocates. — Jeffrey Sonnenfeld, Fortune, 14 July 2026

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor