mule

1 of 3

noun (1)

ˈmyül 

1

a

: a hybrid between a horse and a donkey

especially : the offspring of a male donkey and a mare

b

: a self-sterile plant whether hybrid or not

c

: a usually sterile hybrid

2

: a very stubborn person

3

: a machine for simultaneously drawing and twisting fiber into yarn or thread and winding it into cops

4

slang : a person who smuggles or delivers illicit substances (such as drugs)

mule

2 of 3

noun (2)

: a shoe or slipper without quarter or heel strap compare scuff

mule

3 of 3

noun (3)

variants or less commonly Mule

plural mules also Mules

: moscow mule

Mules are traditionally lime, vodka, and ginger beer served in a copper mug, a very refreshing beverage …

—Santino Mattioli

The marvelous take on a classic mule swaps ginger beer for ginger kombucha … for a crisp, fresh-tasting award-worthy cocktail …

—PR Newswire

Examples of mule in a Sentence

Recent Examples on the Web

Noun

However, his demise has set-up a situation that could pull Maddy into Rue’s storyline just as the young drug mule turned strip club manager has discovered Alamo makes girls disappear. —Sabrina Reed, Forbes.com, 25 May 2026

The crossroads of style and comfort come together with an open-toed mules, all thanks to their chunkier heels and thicker sole padding. —Daisy Maldonado, InStyle, 25 May 2026

The shoe features one strap low across the toes, another higher over the instep and a third acting as an ankle strap, giving the Elsa a more secured fit than the mules and barely-there sandals Swift has worn as of late. —Maggie Clancy, Footwear News, 24 May 2026

From working as a drug mule to pay off her debts to dealer Laurie (Martha Kelly) to now working for crime kingpin/strip club owner Alamo Brown (Adewale Akinnuoye-Agbaje), Rue has been living on the edge. —Saman Shafiq, USA Today, 24 May 2026

Word History

Etymology

Noun (1)

Middle English, from Anglo-French mul, from Latin mulus

Noun (2)

Middle French, a kind of slipper, from Latin mulleus shoe worn by magistrates

Noun (3)

short for moscow mule

First Known Use

Noun (1)

13th century, in the meaning defined at sense 1a

Noun (2)

1562, in the meaning defined above

Noun (3)

1996, in the meaning defined above

Phrases Containing mule

• (as) stubborn as a mule
• Moscow mule
• mule deer
• mule skinner

Rhymes for mule

• boule
• brule
• buhl
• cool
• drool
• fool
• ghoul
• pool
• poul
• rule
• school
• spool

Kids Definition

mule

1 of 2 noun

ˈmyü(ə)l 

1

: the hybrid offspring of a horse and a donkey

especially : the offspring of a male donkey and a female horse

2

: a very stubborn person

3

: a machine that draws and twists fiber into yarn or thread and winds it onto spindles

mule

2 of 2 noun

: a shoe or slipper that is open at the heel

Etymology

Noun

Middle English mule "the offspring of a donkey and a horse," from early French mul (same meaning), from Latin multus (same meaning)

Noun

from early French mule "slipper," from mulleus "a shoe worn by public officials"

Medical Definition

mule

noun

ˈmyü(ə)l 

: a hybrid between a horse and a donkey

especially : the offspring of a male donkey and a mare