LDL

noun

ˌel-(ˌ)dē-ˈel 

: a lipoprotein of blood plasma that is composed of a moderate proportion of protein with little triglyceride and a high proportion of cholesterol and that is associated with increased probability of developing atherosclerosis : bad cholesterol compare hdl

Examples of LDL in a Sentence

Recent Examples on the Web

The main cholesterol and blood fat names to pay attention to are LDL, HDL, and triglycerides. — Gavin Escott, USA Today, 13 Aug. 2026

Your doctor may recommend Lipfendra if your LDL cholesterol remains high despite lifestyle changes and other cholesterol-lowering medications. — Abby Norman, Verywell Health, 5 Aug. 2026

Their anti-inflammatory and antioxidant compounds support heart and brain health, helping lower LDL cholesterol and reduce long-term disease risk. — Randi Gollin, Martha Stewart, 1 Aug. 2026

Many adults currently have LDL levels that are too high, according to the new goals. — Tom Gavin, EverydayHealth.com, 21 July 2026

Word History

Etymology

low-density lipoprotein

First Known Use

1962, in the meaning defined above

Medical Definition

LDL

noun

ˈel-ˈdē-ˈel 

: a lipoprotein of blood plasma that is composed of a moderate proportion of protein with little triglyceride and a high proportion of cholesterol and that is associated with increased probability of developing atherosclerosis

called also bad cholesterol, beta-lipoprotein, low-density lipoprotein

compare hdl, vldl