: a cosmopolitan dipteran fly (Musca domestica) that is often about human habitations and may act as a mechanical vector of diseases (such as typhoid fever)
also : any of various flies of similar appearance or habitat

Examples of housefly in a Sentence

Recent Examples on the Web
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The bake-off could be drawn out to pull the wings off of housefly Powell. Jim Cramer, CNBC, 24 Aug. 2025 Cluster flies may look like houseflies at first glance, but there are a few easy ways to tell them apart. Rae Ford, Martha Stewart, 27 Jan. 2026 Don't worry—there's not enough booze in here to intoxicate a housefly. Josh Miller, Southern Living, 20 Dec. 2025 Larger flies, like houseflies, are after decaying matter such as food waste and pet droppings. Sharon Wu, USA Today, 4 July 2026 See All Example Sentences for housefly

Word History

First Known Use

15th century, in the meaning defined above

Time Traveler
The first known use of housefly was in the 15th century

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Cite this Entry

“Housefly.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/housefly. Accessed 8 Jul. 2026.

Kids Definition

housefly

noun
: a two-winged fly that is common about human living places and may spread disease (as typhoid fever)

Medical Definition

housefly

noun
plural houseflies
: a cosmopolitan dipteran fly of the genus Musca (M. domestica) that is often found about human habitations and may act as a mechanical vector of diseases (as typhoid fever)
also : any of various flies of similar appearance or habitat

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