gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌga-strō-in-ˈte-stə-nᵊl 

-ˈtes(t)-nəl

: of, relating to, affecting, or including both stomach and intestine

Examples of gastrointestinal in a Sentence

Recent Examples on the Web

Two years of eating brownies and pizza as meals, never working out, and entrepreneurial pressure had snowballed into gastrointestinal reflux disease. — Emma Burleigh, Fortune, 4 Oct. 2026

The necropsy indicating chronic gastrointestinal disease in two of the dead belugas certainly raises questions about their condition before transport. — Chicago Tribune, 4 Oct. 2026

These compounds, especially 7-OH, bind to the brain’s mu opioid receptors, which help regulate pain, breathing, gastrointestinal activity and more. — Kristen Rogers, CNN Money, 3 Oct. 2026

The two companies are also collaborating on a clinical trial to evaluate the use of two drugs – sonesitatug vedotin and ivonescimab – in combination to treat certain gastrointestinal cancers. — Chloe Taylor,lee Ying Shan,fred Imbert, CNBC, 28 Sep. 2026

Word History

First Known Use

1831, in the meaning defined above

Phrases Containing gastrointestinal

• gastrointestinal tract

Rhymes for gastrointestinal

• intestinal

Kids Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl 

: of, relating to, or including both stomach and intestine

Medical Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl, -ˈtes(t)-nəl 

: of, relating to, or affecting both stomach and intestine

gastrointestinal distress