Friedel-Crafts reaction

Frie·​del-Crafts reaction | \ frē¦d|elˈkraf(t)s-, ¦freˌd| \

Definition of Friedel-Crafts reaction

: a synthetic reaction in organic chemistry in which anhydrous aluminum chloride acts as the typical catalyst: such as
a : the synthesis of a hydrocarbon (as ethylbenzene) by alkylation of an aromatic hydrocarbon with an alkyl halide
b : the synthesis of a ketone (as benzophenone) by acylation of an aromatic hydrocarbon with an acyl chloride or acid anhydride

Love words?

You must — there are over 200,000 words in our free online dictionary, but you are looking for one that’s only in the Merriam-Webster Unabridged Dictionary.

Start your free trial today and get unlimited access to America's largest dictionary, with:

  • More than 250,000 words that aren't in our free dictionary
  • Expanded definitions, etymologies, and usage notes
  • Advanced search features
  • Ad free!

History and Etymology for Friedel-Crafts reaction

after Charles Friedel †1899 French chemist & James M. Crafts †1917 American chemist

Keep scrolling for more

Learn More about Friedel-Crafts reaction

Statistics for Friedel-Crafts reaction

Cite this Entry

“Friedel-Crafts reaction.” Dictionary, Merriam-Webster, Accessed 15 Jun. 2021.

Style: MLA
MLACheck Mark Icon ChicagoCheck Mark Icon APACheck Mark Icon Merriam-WebsterCheck Mark Icon


Test Your Vocabulary

Name that Thing: Dog Breeds

Name That Thing

Test your visual vocabulary with our 10-question challenge!

Universal Daily Crossword

A daily challenge for crossword fanatics.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!