Friedel-Crafts reaction

Frie·​del-Crafts reaction | \ frē¦d|elˈkraf(t)s-, ¦freˌd|\

Definition of Friedel-Crafts reaction

: a synthetic reaction in organic chemistry in which anhydrous aluminum chloride acts as the typical catalyst: such as
a : the synthesis of a hydrocarbon (as ethylbenzene) by alkylation of an aromatic hydrocarbon with an alkyl halide
b : the synthesis of a ketone (as benzophenone) by acylation of an aromatic hydrocarbon with an acyl chloride or acid anhydride

Love words?

You must — there are over 200,000 words in our free online dictionary, but you are looking for one that’s only in the Merriam-Webster Unabridged Dictionary.

Start your free trial today and get unlimited access to America's largest dictionary, with:

  • More than 250,000 words that aren't in our free dictionary
  • Expanded definitions, etymologies, and usage notes
  • Advanced search features
  • Ad free!

History and Etymology for Friedel-Crafts reaction

after Charles Friedel †1899 French chemist & James M. Crafts †1917 American chemist

Keep scrolling for more

Comments on Friedel-Crafts reaction

What made you want to look up Friedel-Crafts reaction? Please tell us where you read or heard it (including the quote, if possible).


marked by turns or indirection

Get Word of the Day daily email!

Test Your Vocabulary

Summer 2019 Words of the Day Quiz

  • a-bowl-of-peach-sorbet-with-cut-peaches-next-to-it
  • Which is a synonym of desideratum?
Spell It

Can you spell these 10 commonly misspelled words?

Bee Cubed

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!