Ames test

play
noun \ˈāmz-\

Definition of Ames test

  1. :  a test for identifying potential carcinogens by studying their mutagenic effect on bacteria

Origin and Etymology of ames test

Bruce N. Ames born1928 American biochemist


First Known Use: 1976


Medical Dictionary

Ames test

play
noun \ˈāmz-\
variants: also

Ames assay

Medical Definition of Ames test

  1. :  a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial colonies of the genus Salmonella (S. typhimurium) initially lacking the ability to synthesize histidine The compound … produced the highest score ever reported in an Ames test, a standard measure of the cancer-causing potential of toxic chemicals.—Today's Chemist at Work, December 1997 Dimethylnitrosamine … a known animal carcinogen—is usually a potent mutagen in the Ames assay.—Science News, 16 July 1988

Biographical Note for ames test

Ames

,

Bruce Nathan

(born 1928), American biochemist. In 1976 Ames devised his test for carcinogenesis of a substance.


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