Ames test

play
noun \ ˈāmz- \

Definition of Ames test

:a test for identifying potential carcinogens by studying their mutagenic effect on bacteria

Origin and Etymology of ames test

Bruce N. Ames born1928 American biochemist


Medical Dictionary

Ames test

play
noun \ ˈāmz- \
variants: also Ames assay

medical Definition of Ames test

:a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial colonies of the genus Salmonella (S. typhimurium) initially lacking the ability to synthesize histidine
  • The compound … produced the highest score ever reported in an Ames test, a standard measure of the cancer-causing potential of toxic chemicals.
  • Today's Chemist at WorkDecember 1997
  • Dimethylnitrosamine … a known animal carcinogen—is usually a potent mutagen in the Ames assay.
  • Science News16 July 1988

Biographical Note for ames test

  • Ames, Bruce Nathan (born 1928), American biochemist. In 1976 Ames devised his test for carcinogenesis of a substance.

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