Ames test

noun
\ ˈāmz- How to pronounce Ames test (audio) \

Definition of Ames test

: a test for identifying potential carcinogens by studying their mutagenic effect on bacteria

First Known Use of Ames test

1976, in the meaning defined above

History and Etymology for Ames test

Bruce N. Ames born1928 American biochemist

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The first known use of Ames test was in 1976

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Ames test

noun
\ ˈāmz- How to pronounce Ames test (audio) \
variants: also Ames assay

Medical Definition of Ames test

: a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial colonies of the genus Salmonella (S. typhimurium) initially lacking the ability to synthesize histidine The compound … produced the highest score ever reported in an Ames test, a standard measure of the cancer-causing potential of toxic chemicals.Today's Chemist at Work, December 1997 Dimethylnitrosamine … a known animal carcinogen—is usually a potent mutagen in the Ames assay.Science News, 16 July 1988

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