Ames test

play
noun \ˈāmz-\

Definition of Ames test

  1. :  a test for identifying potential carcinogens by studying their mutagenic effect on bacteria

Origin and Etymology of ames test

Bruce N. Ames born1928 American biochemist


Medical Dictionary

Ames test

play
noun \ˈāmz-\
variants: also

Ames assay

Medical Definition of Ames test

  1. :  a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial colonies of the genus Salmonella (S. typhimurium) initially lacking the ability to synthesize histidine The compound … produced the highest score ever reported in an Ames test, a standard measure of the cancer-causing potential of toxic chemicals.—Today's Chemist at Work, December 1997 Dimethylnitrosamine … a known animal carcinogen—is usually a potent mutagen in the Ames assay.—Science News, 16 July 1988

Biographical Note for ames test

Ames

,

Bruce Nathan

(born 1928), American biochemist. In 1976 Ames devised his test for carcinogenesis of a substance.


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