Definition of American wine
: a U.S. wine made from grapes developed from or containing blood of an American wild grape (Vitis labrusca) and grown chiefly in the eastern or middle western part of the U.S.
broadly
: any wine made in the U.S. — compare california wine
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Merriam-Webster unabridged
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Time Traveler for American wine
The first known use of American wine was in 1772
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