achondroplasia

noun

achon·​dro·​pla·​sia ˌā-ˌkän-drə-ˈplā-zh(ē-)ə How to pronounce achondroplasia (audio)
: a genetic disorder that is marked by abnormally slow conversion of cartilage to bone during development resulting in a form of dwarfism characterized by a usually normal torso and shortened limbs and that is usually inherited as an autosomal dominant trait
achondroplastic adjective

Examples of achondroplasia in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
On Tuesday's episode of Little People, Big World, Tori Roloff opened up about how learning of baby Lilah's achondroplasia. Amanda Garrity, Good Housekeeping, 8 Apr. 2020 As a person with achondroplasia, the most common form of dwarfism, dating can be kind of tough when a lot of people are looking for that six-foot-four guy. Taylor Lorenz, New York Times, 18 Mar. 2020 Bayles was born with achondroplasia, a genetic order that results in dwarfism. NBC News, 21 Feb. 2020 And Joss’s story is consistent with voices of the disability community such as Rebecca Cokley, who has explained how her experience with achondroplasia, the most common form of dwarfism, offers her advantages. Washington Post, 17 Jan. 2020 See All Example Sentences for achondroplasia

Word History

Etymology

borrowed from French achondroplasie, from a- a- entry 2 + chondro- chondro- + -plasie -plasia

First Known Use

1881, in the meaning defined above

Time Traveler
The first known use of achondroplasia was in 1881

Browse Nearby Words

Cite this Entry

“Achondroplasia.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/achondroplasia. Accessed 11 Sep. 2025.

Medical Definition

achondroplasia

noun
achon·​dro·​pla·​sia ˌā-ˌkän-drə-ˈplā-zh(ē-)ə How to pronounce achondroplasia (audio)
: a genetic disorder that is marked by abnormally slow conversion of cartilage to bone during development and results in a form of dwarfism characterized by a usually normal torso and shortened limbs

Note: Achondroplasia is usually inherited as an autosomal dominant trait requiring that only one parent passes on a copy of the defective gene on a chromosome other than a sex chromosome. The majority of cases of achondroplasia result from a new spontaneous gene mutation.

compare ateliosis

More from Merriam-Webster on achondroplasia

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!