1
as in to relax
to make less taut
the lead climber loosened the climbing rope so that the other climber could have more room to maneuver
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2
as in to release
to set free (as from slavery or confinement)
the dog ran after the squirrel after he was loosened from the post
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3
as in to unleash
to set free (from a state of being held in check)
once he got to know us better, his inhibitions loosened a bit
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Merriam-Webster unabridged
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