Medical Definition of loose
1a: not rigidly fastened or securely attachedb (1): having worked partly free from attachments <a loose tooth> (2): having relative freedom of movementc: produced freely and accompanied by raising of mucus <a loose cough>
2a: not dense, close, or compact in structure or arrangement <loose connective tissue>b: not solid : watery <loose stools>
3: overactive; specifically : marked by frequent voiding especially of watery stools <loose bowels>
4: not tightly drawn or stretched <loose skin>
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