Simple Definition of mutation

from our Learner's Dictionary

mutation

noun

plural mutations
1
biology : a change in the genes of a plant or animal that causes physical characteristics that are different from what is normal
The cat's short tail is the result of mutation.
The condition is caused by a genetic mutation.
The cat's short tail is the result of a mutation.
mutations in mice
2
: a new form of something that has changed
The building is a mutation of the original design.

Cite this Entry

“Mutation.” Merriam-Webster.com Simple Definition, Merriam-Webster, https://www.merriam-webster.com/simple/mutation. Accessed 22 Jun. 2026.

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