1
: the most important part of something : the part of something that provides its strength and energy
The town's lifeblood has always been its fishing industry.
The neighborhoods are the lifeblood of this city.
2
literary
: a person's blood
the lifeblood that flows through his veins
Cite this Entry
“Lifeblood.” Merriam-Webster.com Simple Definition, Merriam-Webster, https://www.merriam-webster.com/simple/lifeblood. Accessed 17 Apr. 2026.
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