How to Use smallpox in a Sentence

smallpox

noun
  • And for more on smallpox pus, be sure to listen to this week’s episode!
    Popsci Staff, Popular Science, 30 Sep. 2020
  • The threat of the spread of smallpox, which white men carried with them, loomed as well.
    Author: Meagan Flynn, Anchorage Daily News, 27 Mar. 2018
  • Try a place founded when the threats were smallpox and yellow fever.
    Zachary Lewis, cleveland, 25 Mar. 2021
  • That vaccine is the smallpox vaccine, at the same dose adults get.
    The Enquirer, 4 June 2023
  • The only disease that has been wiped out in humans is smallpox.
    Dallas News, 15 July 2021
  • At the time, the threat of smallpox wasn’t something to be taken lightly.
    Annalisa Merelli, Quartz, 15 Feb. 2022
  • Scientists don’t know where the virus in the smallpox vaccine came from.
    The Atlantic Science Desk, The Atlantic, 30 Dec. 2022
  • The world was riddled with smallpox, which killed one-third of all infected.
    Hannah Seo, Discover Magazine, 31 Aug. 2022
  • Mpox is a cousin of smallpox, with both viruses causing rashes on the skin and in the mouth.
    Noor Adatia, Dallas News, 1 June 2023
  • The state's first ice palace was built during a smallpox epidemic.
    Matt McKinney, Star Tribune, 22 Jan. 2021
  • In the days before vaccines, smallpox and polio and measles killed.
    New York Daily News Editorial Board, New York Daily News, 9 July 2025
  • The mpox virus, is a milder version of its relation, smallpox.
    Karen Weintraub, USA TODAY, 23 Feb. 2023
  • Lewis claimed that the odors also caused diseases like plague, smallpox and dysentery.
    Karina Wilson, Smithsonian Magazine, 23 Oct. 2020
  • All eyes land on Cushing’s face, serene, tough, and pockmarked from a bout with smallpox.
    Brian T. Allen, National Review, 12 June 2021
  • The virus is in the same family of viruses as that which causes smallpox.
    Brook Endale, The Enquirer, 26 July 2022
  • Of these, the most common are measles, mumps, rubella, polio, flu, smallpox and tetanus.
    Michael Hiltzik, Los Angeles Times, 14 Sep. 2021
  • Cy Tolliver tries to deny it, but the truth is as plain as smallpox scars.
    Matt Zoller Seitz, Vulture, 18 Dec. 2021
  • The virus originated in Africa and is the cousin of the smallpox virus.
    Cnn Editorial Research, CNN, 5 Sep. 2022
  • The disease was smallpox, a mortal threat to the human race for centuries.
    John Gurda, Milwaukee Journal Sentinel, 31 May 2021
  • Nurses attended to the injured as smallpox swept through the ranks.
    Kinsey Gidick, Travel + Leisure, 8 June 2026
  • The boy didn’t develop lesions, and the smallpox vaccine was born.
    Laura Parker, National Geographic, 16 Sep. 2020
  • Moctezuma’s brother, who took the throne next, died of smallpox, a disease brought by the Spaniards.
    Kiona N. Smith, Ars Technica, 17 Mar. 2022
  • The variola virus that caused smallpox is thought to have been spread among humans for a few thousand years.
    Lorenzino Estrada, AZCentral.com, 9 Dec. 2025
  • Some of the images depict tragedy, like the year that the Lakota people faced smallpox.
    April Wallace, arkansasonline.com, 12 Sep. 2024
  • William Foege, a leader in the global fight to eliminate smallpox, has died.
    Jackie Flynn Mogensen, Scientific American, 26 Jan. 2026
  • The process had a 2% death rate, as compared to the minimal risk modern smallpox vaccine.
    Scott Gleeson, USA TODAY, 2 Dec. 2021
  • Mpox is closely related to smallpox, and infection results in a fever and painful rash that can last for weeks.
    Patrick Jackson, The Conversation, 7 Jan. 2026
  • She was already widowed when her son died of smallpox in 1879, at the age of twenty-four.
    Anika Burgess, New Yorker, 7 Mar. 2026
  • The shot was approved for use against smallpox and monkeypox in 2019.
    Katherine J. Wu, The Atlantic, 10 Aug. 2022
  • In the 1800s, smallpox vaccine was shipped across the channel to France.
    Albert Bourla, Forbes, 7 Mar. 2022

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'smallpox.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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