How to Use microenvironment in a Sentence
microenvironment
noun-
Light changes the microenvironment inside the frame, causing swelling and contraction that ages the work very quickly.
—David Walters, The Cut, 20 Oct. 2017
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Their presence in both habitats suggests the species occupies a range of microenvironments within its canyon home.
—Ryan Brennan, Kansas City Star, 20 Feb. 2026
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What is the tumor microenvironment?
—Charles J. Dimitroff, The Conversation, 12 June 2026
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This means phytoplankton can establish a microenvironment in the water around them.
—Katherine Bourzac, Quanta Magazine, 15 Sep. 2025
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The livers began as stem cells that are cultivated into skin and vascular cells that form a complete microenvironment.
—Caroline Delbert, Popular Mechanics, 3 June 2020
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Along with its many tricks to avoid detection, tumors build microenvironments around themselves that are toxic to immune cells, draining them of energy.
—Michael Irving, New Atlas, 20 Sep. 2024
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The complex terrain creates isolated pockets of habitat — a cave system here, a rocky outcrop there — each with its own microenvironment.
—Ryan Brennan, Charlotte Observer, 25 Feb. 2026
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These bacteria produce lactic acid, which creates an acidic microenvironment that allows only a few other bacteria and yeasts to grow.
—ABC News, 4 Apr. 2021
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There are many different components in the microenvironment that are affected.
—Bradley J. Fikes, sandiegouniontribune.com, 18 Sep. 2017
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Solid tumors are more difficult to access, and are often contained in a microenvironment that dampens the body’s immune response.
—Scientific American, 1 Oct. 2021
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When tumor cells switch to glycolic respiration, a byproduct makes the tumor microenvironment acidic.
—David Robert Grimes, Scientific American, 1 July 2024
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That’s because the microenvironment (the area directly around the tumor) consists of molecules and blood vessels that have become tainted.
—Joshua Hawkins, BGR, 6 Oct. 2022
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Together, these features create what scientists refer to as the tumor microenvironment, where cancer cells live and interact with the body.
—Charles J. Dimitroff, The Conversation, 12 June 2026
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The fibers create a life-like microenvironment in which the cells can function and interact with each other just like normal cells would, while the hydrogel protects them from the body's immune response.
—Breanna Draxler, Discover Magazine, 2 Apr. 2013
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The cells either sequester or export nitric oxide, depending on oxygen traffic between them and tissue in the microenvironment.
—Byandrew Zaleski, science.org, 3 July 2024
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So far, these two methods have not worked as well as hoped—stem cells turn out to be difficult to manipulate, and the microenvironment of spinal-cord fluid is extremely complicated.
—Isaac Chotiner, The New Yorker, 12 Aug. 2021
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Working with the spleens of primates (macaques), the team engineered microenvironments within the test organs to support human pancreatic islets.
—Discover Magazine, 23 May 2025
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The tumor microenvironment allows cancer to withstand an onslaught from a body’s natural immune defenses.
—Charles J. Dimitroff, The Conversation, 12 June 2026
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The sum total of the conditions inside our bodies, called the microenvironment, plays an important though dimly understood role in regulating how our cells react.
—Nathaniel Scharping, Discover Magazine, 29 Mar. 2017
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Every valley, stream and forest, composes a microenvironment.
—Steve Meyer, Anchorage Daily News, 2 Oct. 2022
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This shows that although bacterial organisms come from common sources, each of the microenvironments somehow selects for distinct microbes, Gilbert said.
—Tracy Staedter, Fox News, 30 May 2017
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The spongy structure is organized into specialized microenvironments called niches.
—Mrigakshi Dixit, Interesting Engineering, 19 Nov. 2025
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The focus is no longer just on attacking cancer cells directly, but also navigating the tumor microenvironment in order to protect immune cells in their mission to kill cancer cells.
—Charles J. Dimitroff, The Conversation, 12 June 2026
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AnapTh, a fluorescent amino acid, shifts its emission spectrum depending on the surrounding microenvironment.
—Aamir Khollam, Interesting Engineering, 11 Sep. 2025
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The researchers found that the cities’ chemical microenvironments increase calcite dissolution.
—Damien Pine, Scientific American, 15 May 2026
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Factors other than mutation, such as epigenetic changes (alterations in how a gene is expressed) in a primary tumor cell—or the details of its microenvironment—were more likely to blame for metastasis.
—Jeffrey P. Townsend, Scientific American, 1 Apr. 2018
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Since the tumor microenvironment can affect behavior of the tumor cells and their response to treatments, these racial differences could impact tumor biology and disease progression.
—Philly.com, 23 Feb. 2018
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Lastly, solid tumors possess an extensively inhospitable microenvironment for the T cells.
—William A. Haseltine, Forbes, 17 Mar. 2023
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One major challenge is the tumor microenvironment — a network of cells and signals surrounding a tumor that can act as a protective shield for cancer and prevent immunotherapy from working effectively.
—Ashley MacKin Solomon, San Diego Union-Tribune, 9 June 2026
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Reprogrammed macrophages also alter the tumor microenvironment, activating other immune cells.
—William A. Haseltine, Forbes.com, 7 Jan. 2026
Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'microenvironment.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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