How to Use methylation in a Sentence

methylation

noun
  • During methylation, a methyl group in the epigenome turns genes off.
    Tad Friend, New Yorker, 4 Aug. 2025
  • Lab tests can tell how old a human is just from the pattern of methylation.
    James Gorman, Star Tribune, 14 Nov. 2020
  • Other labs look at changes in chemical tags called methylation groups that can turn genes on or off.
    Joanna Thompson, Quanta Magazine, 26 Jan. 2023
  • The other was a methylation test called GrimAge.
    Tad Friend, New Yorker, 4 Aug. 2025
  • The researchers then focused on how these methylation patterns were passed down to the next generation.
    Jonathan Wosen, STAT, 7 Feb. 2023
  • This allowed the scientists to track where methylation occurs.
    New Atlas, 2 July 2025
  • This can be done through chemical processes methylation, which turns genes on, or demethylation, which turns genes off.
    Allison Deangelis, STAT, 4 Jan. 2024
  • The researchers found that the pattern of methylation suggested that the same genes may be involved in both processes.
    James Gorman, New York Times, 9 Nov. 2020
  • The researchers said the pattern of methylation suggested that the same genes may be involved in both processes.
    James Gorman, Star Tribune, 14 Nov. 2020
  • Some changes that happen with DNA methylation may age the body faster, while others may slow aging down.
    Lisa Rapaport, EverydayHealth.com, 29 July 2024
  • First, the soil has ample organic matter, providing a deep store of energy in the form of carbon to fuel methylation.
    Eve-Lyn Hinckley, The Conversation, 20 Aug. 2025
  • Specially, methylation marks — chemical marks on DNA that change with age.
    Wyatte Grantham-Philips, USA TODAY, 13 July 2020
  • Effects were variable across neurons; only about 10% to 30% of cells showed major methylation changes.
    New Atlas, 11 Sep. 2025
  • And while correlation between methylation and gene expression was strong, causality was not proven.
    New Atlas, 16 Aug. 2025
  • Further, the study did not directly prove which methylation changes caused what transcriptomic changes; that would require further research.
    New Atlas, 11 Sep. 2025
  • Grail chose to focus entirely on methylation, a chemical change to the DNA, not the code itself.
    Matthew Herper, STAT, 19 May 2021
  • Epigenetic changes, such as methylation of genes involved in the immune response, were also documented.
    Scott E. Solomon, STAT, 22 Apr. 2026
  • One way this happens is by methylation, or the addition of methyl groups to a DNA molecule's chemical structure.
    Leslie Nemo, Discover Magazine, 20 Nov. 2019
  • And this one appears to enhance melatonin synthesis via SAM methylation—a novel pathway.
    Lucy Notarantonio, MSNBC Newsweek, 21 June 2025
  • The addition of methyl tags to DNA bases, called methylation, is an epigenetic change that allows some genes to be transcribed while others are not.
    Veronique Greenwood, Discover Magazine, 12 July 2011
  • To quantify these changes, the team used epigenetic clocks, tools that estimate biological age based on methylation patterns.
    Brian Mastroianni, Health, 10 Mar. 2025
  • Among other mechanisms involved in a child’s growth, folate aids the epigenetic process of methylation and may help prepare the fetus for its future environment.
    Molly Glick, Discover Magazine, 28 Jan. 2022
  • For people who do not have a problem converting regular vitamins into their active form or absorbing them, methylation will probably not have much of an impact.
    Allison Futterman, Discover Magazine, 7 Jan. 2025
  • Belsky’s team then analyzed methylation marks — signs of epigenetic changes — on the DNA, looking for symptoms of aging.
    Sandee Lamotte, CNN, 10 Feb. 2023
  • Researchers used a method called DNA methylation to measure aging biomarkers in systems including the heart and metabolism.
    Lisa Rapaport, EverydayHealth.com, 29 July 2024
  • The company is using a technology that looks at methylation—or how genes are expressed—combined with machine-learning algorithms to classify cancer signals from non-cancer ones.
    Sarah Elizabeth Richards, Smithsonian Magazine, 7 Feb. 2020
  • Scientists found that the methylation marks regulating Ankrd26 and Ldlr went through reprogramming, too.
    Jonathan Wosen, STAT, 7 Feb. 2023
  • Methyl-seq, in which certain chemical modifications of the bases that make up genes are detected, is gaining in utility as the role of methylation in gene regulation is being understood.
    Demaris Mills, Forbes, 24 June 2022
  • Overall, the twins who went vegan saw a significant reduction in markers of biological age based on changes in DNA methylation.
    Lisa Rapaport, EverydayHealth.com, 29 July 2024
  • One common type of epigenetic modification is called DNA methylation.
    Amery Treble-Barna, The Conversation, 9 Dec. 2025

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'methylation.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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