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uncoupler

noun

un·​cou·​pler ˈən-ˈkəp-(ə-)lər How to pronounce uncoupler (audio)
: an agent that dissociates two integrated series of chemical reactions
especially : one that prevents the formation of ATP in oxidative phosphorylation in mitochondria by dissociating the reactions of phosphorylation from those concerned with electron transport and oxidation

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Cite this Entry

“Uncoupler.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/uncoupler. Accessed 27 Nov. 2025.

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