Medical Dictionary

taxane

noun tax·ane \ ˈtak-ˌsān \

medical Definition of taxane

:any of various tricyclic compounds (as docetaxel and paclitaxel) with anticancer activity that are obtained from yew trees (genus Taxus) or are made synthetically
Note: Taxanes act by binding tubulin, thereby promoting microtubule formation and arresting cell division.
  • The taxanes are an important new class of anticancer agents that exert their cytotoxic effects through a unique mechanism.
  • —Eric K. Rowinsky and Ross C. DonehowerThe New England Journal of Medicine13 Apr. 1995
  • Some cancers, though, are armored against taxanes: Their cell membranes carry a multiple-drug-resistance pump that identifies taxanes as a threat and pumps them out before they can infiltrate the cell.
  • —Jonathan FaheyForbes28 May 2001

Seen and Heard

What made you want to look up taxane? Please tell us where you read or heard it (including the quote, if possible).

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

to conform or adhere

Get Word of the Day daily email!

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!