sliding filament hypothesis


slid·​ing filament hypothesis ˈslīd-iŋ- How to pronounce sliding filament hypothesis (audio)
: a theory in physiology holding that muscle contraction occurs when the actin filaments next to the Z line at each end of a sarcomere are drawn toward each other between the thicker myosin filaments more centrally located in the sarcomere by the projecting globular heads of myosin molecules that form temporary attachments to the actin filaments and become detached when the actin filaments move in the opposite directions toward the ends of the sarcomere

called also sliding filament theory

see crossbridge

Dictionary Entries Near sliding filament hypothesis


sliding filament hypothesis

sliding microtome

Cite this Entry

“Sliding filament hypothesis.” Medical Dictionary, Merriam-Webster, Accessed 25 Feb. 2024.

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