re·​frac·​to·​ri·​ness ri-ˈfrak-t(ə-)rē-nəs How to pronounce refractoriness (audio)
: the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation

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“Refractoriness.” Medical Dictionary, Merriam-Webster, Accessed 28 Jan. 2023.

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