progressive multifocal leukoencephalopathy

noun

Medical Definition of progressive multifocal leukoencephalopathy

: a progressive and often fatal demyelinating disease of the central nervous system that typically affects immunocompromised individuals and that is characterized especially by muscle weakness and loss of coordination with impairments in speech, vision, and cognitive function and that commonly progresses to paralysis and coma

Note: Progressive multifocal leukoencephalopathy is caused by reactivation in the body of a latent virus of the genus Polyomavirus (species JC polyomavirus) which destroys the myelin-producing oligodendrocytes of the central nervous system.

Comments on progressive multifocal leukoencephalopathy

What made you want to look up progressive multifocal leukoencephalopathy? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

one from the Upper Peninsula of Michigan

Get Word of the Day daily email!

Test Your Vocabulary

Musical Words Quiz

  • gramophone
  • Which word describes a musical performance marked by the absence of instrumental accompaniment?
How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!