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Frequent Urination Frequent urination, or polyuria, often accompanies excessive thirst.—Daniel Combs, Verywell Health, 16 May 2025 In more extreme cases, hypercalcemia (high serum calcium) or hypercalciuria (high urine calcium) can cause poor muscle tone, renal insufficiency, weight loss, fatigue, polyuria, heart arrhythmias, and a higher risk of heart disease.—Casey Seiden, Parents, 30 May 2024 Nocturnal polyuria is voiding a high urine volume at night.—Sarah Bradley, Health, 17 Nov. 2023 What is polyuria?—Sarah Bradley, Health.com, 19 Oct. 2021
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