Medical Dictionary

platelet-activating factor

noun plate·let-ac·ti·vat·ing factor \ -ˌak-tə-ˌvāt-iŋ- \

medical Definition of platelet-activating factor

: phospholipid that is produced especially by mast cells and basophils, causes the aggregation of blood platelets and the release of blood-platelet substances (as histamine or serotonin), and is a mediator of inflammation (as in asthma) abbreviation PAF

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