Medical Dictionary

photoaffinity labeling


Medical Definition of photoaffinity labeling

  1. :  a technique of attaching a label to the active site of a large molecule and especially a protein by using a molecule which binds loosely and reversibly to the large molecule's active site and which has an inactive part that can be converted by photolysis to a highly reactive form causing the complex of the large substrate molecule and the loosely attached label to bind more permanently

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to cast off or become cast off

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