Medical Dictionary

phosphorothioate

noun phos·pho·ro·thio·ate \ ˌfäs-fə-rō-ˈthī-ō-ˌāt \

medical Definition of phosphorothioate

: an oligonucleotide in which the oxygen atom normally linking two consecutive nucleotides has been replaced with sulfur and which resists degradation by cellular enzymes — compare phosphodiester

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