pharmacogenomics

noun

phar·​ma·​co·​ge·​no·​mics ˌfär-mə-kō-jē-ˈnō-miks How to pronounce pharmacogenomics (audio)
plural in form but singular in construction
: the science concerned with understanding how genetic differences among individuals cause varied responses to the same drug and with developing drug therapies to compensate for these differences
The Human Genome Project heralds new opportunities for using genetic information to individualize drug therapy, called pharmacogenomics.Kathryn A. Phillips et al.
pharmacogenomic adjective
The Food and Drug Administration (FDA) has altered drug labels and issued warnings about pharmacogenomic variation affecting drug response … Liewei Wang et al.

Word History

First Known Use

1997, in the meaning defined above

Time Traveler
The first known use of pharmacogenomics was in 1997

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Cite this Entry

“Pharmacogenomics.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/pharmacogenomics. Accessed 10 Sep. 2025.

Medical Definition

pharmacogenomics

noun, plural in form but singular in construction
phar·​ma·​co·​ge·​no·​mics -jē-ˈnō-miks How to pronounce pharmacogenomics (audio)
: the science concerned with understanding how genetic differences among individuals cause varied responses to the same drug and with developing drug therapies to compensate for these differences
Drug companies … are collecting the genetic know-how to make medicines tailored to specific genes—an effort called pharmacogenomics. In the years to come, your pharmacist may hand you one version of a blood pressure drug, based on your unique genetic profile, while the guy in line behind you gets a different version of the same medicine.Kathryn Brown, Scientific American
pharmacogenomic adjective
Pharmacogenomic testing of individuals may prevent adverse drug reactions and save both lives and money. Sandra Soo-Jin Lee et al., Science
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