Medical Dictionary

pegylation

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noun peg·y·la·tion \ˌpeg-ə-ˈlā-shən\
variants: or

PEGylation

Medical Definition of pegylation

  1. :  the attachment of polyethylene glycol chains to a molecule When PEG's are attached to other molecules in a process known as pegylation, the body also ignores the attached molecules, thus providing an invisibility clock to drugs that otherwise would be dismantled by the body's immune defenses or flushed out by the kidneys.—Kenneth Chang, The New York Times, 27 Feb. 2001

pegylated

\ˈpeg-ə-ˌlāt-əd\ play or

PEGylated

adjective In the pegylated form of interferon, the interferon alfa molecule is linked to a polyethylene glycol molecule to ensure sustained interferon concentrations after single weekly injections.—Jean-Michel Pawlotsky, The New England Journal of Medicine, 29 July 2004

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