Medical Dictionary

pegylation

noun peg·y·la·tion \ ˌpeg-ə-ˈlā-shən \
variants: or PEGylation

medical Definition of pegylation

:the attachment of polyethylene glycol chains to a molecule
  • When PEG's are attached to other molecules in a process known as pegylation, the body also ignores the attached molecules, thus providing an invisibility clock to drugs that otherwise would be dismantled by the body's immune defenses or flushed out by the kidneys.
  • —Kenneth ChangThe New York Times27 Feb. 2001

pegylated

play \ˈpeg-ə-ˌlāt-əd\ or PEGylated adjective
    • In the pegylated form of interferon, the interferon alfa molecule is linked to a polyethylene glycol molecule to ensure sustained interferon concentrations after single weekly injections.
    • —Jean-Michel PawlotskyThe New England Journal of Medicine29 July 2004

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