pegylation

noun
peg·​y·​la·​tion | \ ˌpeg-ə-ˈlā-shən How to pronounce pegylation (audio) \
variants: or PEGylation

Medical Definition of pegylation

: the attachment of polyethylene glycol chains to a molecule When PEG's are attached to other molecules in a process known as pegylation, the body also ignores the attached molecules, thus providing an invisibility clock to drugs that otherwise would be dismantled by the body's immune defenses or flushed out by the kidneys.— Kenneth Chang, The New York Times, 27 Feb. 2001

Other Words from pegylation

pegylated \ ˈpeg-​ə-​ˌlāt-​əd How to pronounce pegylation (audio) \ or PEGylated adjective
In the pegylated form of interferon, the interferon alfa molecule is linked to a polyethylene glycol molecule to ensure sustained interferon concentrations after single weekly injections. — Jean-Michel Pawlotsky, The New England Journal of Medicine, 29 July 2004

Learn More About pegylation

Dictionary Entries Near pegylation

pegfilgrastim

pegylation

pelage

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Cite this Entry

“Pegylation.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/pegylation. Accessed 16 Jan. 2022.

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