medical Definition of peau d'orange
:thickened, dimpled skin that resembles the rind of an orange and is often associated with some forms of breast cancer
- There was a mass, 6 to 7 cm in diameter, in the upper outer quadrant of the right breast … and the overlying skin had peau d'orange changes, without erythema.
- —José Baselga et al., The New England Journal of Medicine, 24 May 2012
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