SINCE 1828
open reading frame
noun
open read·ing frame
| \ -ˈrēd-iŋ-
\
\
Medical Definition of open reading frame
: a reading frame that does not contain a nucleotide triplet which stops translation before formation of a complete polypeptide
—abbreviation ORF
Comments on open reading frame
What made you want to look up open reading frame? Please tell us where you read or heard it (including the quote, if possible).
Test Your Vocabulary
Original Meanings Quiz
-
- Which of the following is the earliest known sense of the word awe?
Can you spell these 10 commonly misspelled words?
TAKE THE QUIZ
Test Your Knowledge - and learn some interesting things along the way.
TAKE THE QUIZLove words? Need even more definitions?
Merriam-Webster unabridgedWords at Play
Ask the Editors
Word Games
-
Original Meanings Quiz
A quiz for the pedantic and those annoyed by them!
Take the quiz -
A Green Quiz
How many questions can you answer about the word "green"?
Take the quiz -
Spell It
Can you spell these 10 commonly misspelled words?
Take the quiz -
SCRABBLE® Sprint
SCRABBLE® fans, sharpen your skills!
Play the game
Share open reading frame
Resources for open reading frame