Medical Dictionary

nitrosourea

noun ni·tro·so·urea \ -yu̇-ˈrē-ə \

medical Definition of nitrosourea

: any of a group of lipid-soluble antineoplastic drugs that function as alkylating agents with the ability to cross the blood-brain barrier
  • The response of most gliomas to chemotherapy is limited, but the addition of nitrosourea or procarbazine to radiation therapy increases the survival of some patients with high-grade gliomas.
  • Scientfic American Medicine BulletinMay 1995
— see carmustine

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