Medical Definition of nitrosourea
: any of a group of lipid-soluble antineoplastic drugs that function as alkylating agents with the ability to cross the blood-brain barrier The response of most gliomas to chemotherapy is limited, but the addition of nitrosourea or procarbazine to radiation therapy increases the survival of some patients with high-grade gliomas.—Scientfic American Medicine Bulletin, May 1995—see carmustine
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