mescaline

noun

mes·​ca·​line ˈme-skə-lən How to pronounce mescaline (audio) ˈme-skə-ˌlēn How to pronounce mescaline (audio)
: a hallucinatory crystalline alkaloid C11H17NO3 that is the chief psychoactive principle in peyote buttons
Natural psychedelics such as mescaline or psilocybin are found in plants considered sacred since ancient times.Luis Alberto Henríquez-Hernández et al.

Examples of mescaline in a Sentence

Recent Examples on the Web
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As part of the case, which will be heard in the fall, the court will consider narrowing a landmark 1990 decision over the spiritual use of peyote, a cactus that contains a hallucinogen called mescaline. Lindsay Whitehurst, Chicago Tribune, 20 Apr. 2026 As part of the case, the court will consider narrowing a landmark 1990 decision over the spiritual use of peyote, a cactus that contains a hallucinogen called mescaline. ABC News, 20 Apr. 2026 Federal scheduling currently has drugs like LSD, marijuana, mescaline, DMT, and psilocybin classified as Schedule I narcotics. Rafael Perez, Oc Register, 3 Sep. 2025 The proposition also decriminalized possession, personal use, growing and sharing of five psychedelic substances: psilocybin, psilocin, DMT, ibogaine and mescaline. Elliott Wenzler, The Denver Post, 3 Mar. 2025 See All Example Sentences for mescaline

Word History

First Known Use

1896, in the meaning defined above

Time Traveler
The first known use of mescaline was in 1896

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Cite this Entry

“Mescaline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mescaline. Accessed 27 Apr. 2026.

Kids Definition

mescaline

noun
mes·​ca·​line ˈmes-kə-lən How to pronounce mescaline (audio)
-ˌlēn
: a drug that is obtained from the peyote cactus and causes hallucinations

Medical Definition

mescaline

noun
mes·​ca·​line ˈmes-kə-lən How to pronounce mescaline (audio) -ˌlēn How to pronounce mescaline (audio)
: a hallucinatory crystalline alkaloid C11H17NO3 that is the chief psychoactive principle in peyote buttons

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