mega·du·o·de·num | \ ˌmeg-ə-ˌd(y)ü-ə-ˈdē-nəm; -d(y)u̇-ˈäd-ᵊn-əm 
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\ plural megaduodena\ -ˈdē-nə; -ᵊn-ə \ or megaduodenums
\ or megaduodenumsMedical Definition of megaduodenum
: a congenital or acquired dilation and elongation of the duodenum with hypertrophy of all layers that presents as a feeling of gastric fullness, epigastric pain, belching, heartburn, and nausea with vomiting sometimes of food eaten 24 hours before
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