mastocytosis

noun

mas·​to·​cy·​to·​sis -ˈtō-səs How to pronounce mastocytosis (audio)
plural mastocytoses -ˌsēz How to pronounce mastocytosis (audio)
: excessive proliferation of mast cells in the tissues
specifically : a rare variable disorder marked by the abnormal proliferation and accumulation of mast cells in the skin, bone marrow, or internal organs

Note: A benign, cutaneous form of mastocytosis (see urticaria pigmentosa) occurs typically in children and may affect many areas of the skin. A less common, systemic form, usually of adults may affect multiple organs (such as the liver, spleen, and intestine), lymph nodes, and bone marrow and typically occurs as a benign, slowly progressing, indolent condition with normal life expectancy but may sometimes occur as an aggressive, often fatal condition.

The most common form of mastocytosis in childhood is urticaria pigmentosa. In this disorder, mast cells accumulate in the skin, forming reddish-brown papules and plaques … Melissa M. Burnett et al., The New England Journal of Medicine
Systemic mastocytosis is characterised by diffuse mast-cell infiltration of multiple organs and may affect approximately 10% of all patients with mastocytosis. Takashi Koide et al., The Lancet

Dictionary Entries Near mastocytosis

Cite this Entry

“Mastocytosis.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/mastocytosis. Accessed 3 Feb. 2023.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!


Words Named After People

  • name tags
  • Namesake of the leotard, Jules Léotard had what profession?
Spell It

Hear a word and type it out. How many can you get right?

TAKE THE QUIZ
Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?

PLAY