mastocytosis

noun
mas·to·cy·to·sis | \ -ˈtō-səs \
plural mastocytoses\-ˌsēz \

Medical Definition of mastocytosis 

: excessive proliferation of mast cells in the tissues specifically : a rare variable disorder marked by the abnormal proliferation and accumulation of mast cells in the skin, bone marrow, or internal organs

Note: A benign, cutaneous form of mastocytosis ((see urticaria pigmentosa)) occurs typically in children and may affect many areas of the skin. A less common, systemic form, usually of adults may affect multiple organs (such as the liver, spleen, and intestine), lymph nodes, and bone marrow and typically occurs as a benign, slowly progressing, indolent condition with normal life expectancy but may sometimes occur as an aggressive, often fatal condition.

The most common form of mastocytosis in childhood is urticaria pigmentosa. In this disorder, mast cells accumulate in the skin, forming reddish-brown papules and plaques …
—Melissa M. Burnett et al., The New England Journal of Medicine, 20 Dec. 2007 Systemic mastocytosis is characterised by diffuse mast-cell infiltration of multiple organs and may affect approximately 10% of all patients with mastocytosis. —Takashi Koide et al., The Lancet, 15 June 2002

Learn More about mastocytosis

Share mastocytosis

Comments on mastocytosis

What made you want to look up mastocytosis? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

a magnificent or impressive array

Get Word of the Day daily email!

Test Your Vocabulary

Name that Food Quiz

Name That Thing

Test your visual vocabulary with our 10-question challenge!

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!