lupus

noun

lu·​pus ˈlü-pəs 

1

: any of several diseases characterized by skin lesions

especially : systemic lupus erythematosus sense 2

2

Lupus astronomy : a southern constellation that is visible between the constellations of Scorpius and Centaurus and that is represented by the figure of a wolf

Above Lupus lies Scorpius, one of the few constellations whose star pattern actually suggests the object that it is named for. In the myths, the scorpion was assigned by Artemis, the hunting goddess, to kill Orion, far across the sky.

—Don Moser

Examples of lupus in a Sentence

Recent Examples on the Web

Patients might be women in their 30s with an autoimmune disease like lupus or people of any age exposed to such toxins as methamphetamines or, in the past, the fen-phen appetite suppressant drug of the 1990s, later withdrawn after being linked to heart disease. — Elizabeth Cooney, STAT, 26 June 2026

Harvard Health reports the associations may stretch well beyond the gut, from autoimmune diseases like lupus, type 1 diabetes and multiple sclerosis to chronic fatigue, fibromyalgia, arthritis, allergies, asthma, acne, obesity and even mental illness. — Ryan Brennan, Sacbee.com, 24 June 2026

According to MedlinePlus, an online health resource run by the National Library of Medicine, lupus is a chronic autoimmune condition that can affect many parts of the body, including the skin, joints, kidneys, lungs, heart, blood vessels, nervous system and digestive system. — ABC News, 23 June 2026

That’s because the same species, Canis lupus, ranges from Alaska through Canada into the upper West and the Midwest. — Natalie Krebs, Outdoor Life, 11 June 2026

Word History

Etymology

Middle English, from Medieval Latin, from Latin, wolf

First Known Use

14th century, in the meaning defined at sense 1

Phrases Containing lupus

• lupus erythematosus
• systemic lupus erythematosus

Rhymes for lupus

• croupous

Medical Definition

lupus

noun

lu·​pus ˈlü-pəs 

: any of several diseases (as lupus vulgaris or systemic lupus erythematosus) characterized by skin lesions