Medical Definition of loperamide
: a synthetic antidiarrheal agent that slows intestinal peristalsis and is taken orally in the form of its hydrochloride C29H33ClN2O2·HCl to control acute nonspecific diarrhea or chronic diarrhea associated with inflammatory bowel disease or to reduce fecal volume discharged from ileostomies ◆Loperamide is marketed under the trademark Imodium.
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