Medical Dictionary

isoelectric point


Medical Definition of isoelectric point

  1. :  the point or narrow range on a pH scale at which an amphoteric molecule or surface carries no electrical charge, or in which the negative and positive charges are equal resulting in a net zero charge :  the pH at which an amphoteric molecule will not migrate in an electrical field <Proteins migrate to the pH region corresponding to their isoelectric point, where they become immobilized because of a zero net charge.—David R. Burwasser, Technical Survey, 20 Mar. 1982> <Pyrogenic exotoxin C is characterized by an isoelectric point of 7.2 …—Steven E. Schutzer et al., Science, 15 April 1983>—see isoelectric focusing

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