Medical Dictionary

isoelectric point

noun

medical Definition of isoelectric point

:the point or narrow range on a pH scale at which an amphoteric molecule or surface carries no electrical charge, or in which the negative and positive charges are equal resulting in a net zero charge :the pH at which an amphoteric molecule will not migrate in an electrical field
  • Proteins migrate to the pH region corresponding to their isoelectric point, where they become immobilized because of a zero net charge.
  • —David R. BurwasserTechnical Survey20 Mar. 1982
  • Pyrogenic exotoxin C is characterized by an isoelectric point of 7.2 …
  • —Steven E. Schutzer et al.Science15 April 1983
— see isoelectric focusing

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