Medical Dictionary

isocitrate dehydrogenase

noun isocitrate de·hy·dro·ge·nase \ -ˌdē-(ˌ)hī-ˈdräj-e-ˌnās, -(ˈ)dē-ˈhī-drə-jə-, -ˌnāz \

medical Definition of isocitrate dehydrogenase

: either of two enzymes which catalyze the oxidation of isocitric acid to alpha-ketoglutaric acid (as in the Krebs cycle) and of which one uses NAD as an electron acceptor and the other NADP called also isocitric dehydrogenase

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