immunoproliferative small intestinal disease

noun

Medical Definition of immunoproliferative small intestinal disease

: a lymphoma that arises in the small intestine, is marked especially by abdominal pain, diarrhea, and malabsorption, and that chiefly affects individuals in Mediterranean regions

Note: Immunoproliferative small intestinal disease is associated with the secretion by proliferating plasma cells of truncated IgA heavy chains without the accompanying light chains.

abbreviation IPSID

called also alpha chain disease, Mediterranean lymphoma

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