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ichthyosis hys·trix gra·vi·or | \ -ˈhis-triks-ˈgrav-ē-ˌȯr 
, -ˈgräv- \
, -ˈgräv- \Medical Definition of ichthyosis hystrix gravior
: a rare hereditary disease characterized by the formation of brown, verrucose, and often linear lesions of the skin
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