histidine

noun

his·​ti·​dine ˈhi-stə-ˌdēn How to pronounce histidine (audio)
: a crystalline essential amino acid C6H9N3O2 formed by the hydrolysis of most proteins

Examples of histidine in a Sentence

Recent Examples on the Web
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And Susie points to recent research that highlights how bone broth contains amino acids like glutamine, glycine, proline, histidine and arginine, which can collectively be helpful with immune function, tissue repair and muscle recovery. Daryl Austin, USA Today, 6 June 2026 The other six essential amino acids required to build and repair muscle are histidine, lysine, methionine, phenylalanine, threonine, and tryptophan. Shimite Obialo, Forbes.com, 26 May 2026 While in this energized state, the lignin functions as a photoacid, transferring protons to the histidine inside the solid material. Mrigakshi Dixit, Interesting Engineering, 10 Nov. 2025 Nine essential amino acids—histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine—are available only through foods or supplements. Stacey Colino, Time, 27 May 2025 High-quality protein is any protein that contains all of the nine essential amino acids (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine) that our bodies don’t make on their own. USA TODAY, 2 July 2023 This supplement also contains 100% of your daily value of folate, 3,000 percent of your daily value of B12, and the amino acid L-histidine. Tamar Kane, Verywell Health, 5 Feb. 2023

Word History

Etymology

International Scientific Vocabulary hist- + -idine

First Known Use

1896, in the meaning defined above

Time Traveler
The first known use of histidine was in 1896

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Cite this Entry

“Histidine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/histidine. Accessed 5 Jul. 2026.

Medical Definition

histidine

noun
his·​ti·​dine ˈhis-tə-ˌdēn How to pronounce histidine (audio)
: a crystalline essential amino acid C6H9N3O2 formed by the hydrolysis of most proteins
abbreviation His

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