: a crystalline glycoside C28H34O15 found in most citrus fruits and especially in orange peel

Examples of hesperidin in a Sentence

Recent Examples on the Web
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Orange juice contains compounds like hesperidin and naringenin, which may help reduce inflammation, support heart health, and regulate blood sugar. Randi Gollin, Martha Stewart, 17 May 2026 Both juices contain antioxidants that protect cells from damage, including beta-carotene in carrot juice and hesperidin in orange juice. Caitlin Beale, Health, 5 Jan. 2026

Word History

Etymology

borrowed from French hespéridine, from Hespéridées (vernacular form of New Latin Hesperideae, Linnaean taxon that included Citrus and other genera, from Latin Hesperid-, stem of Hesperides hesperides + New Latin -eae, suffix of groups, feminine plural of -eus -eous) + -ine -in entry 1

Note: The substance was first isolated by "the pharmacist Lebreton" (le pharmacien Lebreton, biographical details uncertain), who reported it in "Sur la matière cristalline des orangettes, et analyse de ces fruits non encore développés, famille des Hespéridées," Journal de pharmacie et des sciences accessoires, No. 8, 14e année, juillet 1828, pp. 377-92. See note at hesperidium.

First Known Use

1838, in the meaning defined above

Time Traveler
The first known use of hesperidin was in 1838

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Cite this Entry

“Hesperidin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hesperidin. Accessed 26 Aug. 2026.

Medical Definition

hesperidin

noun
: a crystalline glycoside C28H34O15 found in most citrus fruits and especially in orange peel
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