Medical Dictionary

fibrodysplasia ossificans progressiva

noun fi·bro·dys·pla·sia os·sif·i·cans pro·gres·si·va \ ˌfī-brō-di-ˈsplā-zh(ē-)ə-ä-ˈsi-fə-ˌkanz-prə-ˈgre-sə-və \

medical Definition of fibrodysplasia ossificans progressiva

: a rare hereditary disorder that is characterized by the progressive ossification of muscle and connective tissue and that is inherited as an autosomal recessive trait
  • Fibrodysplasia ossificans progressiva in humans appears to be the only known example of a naturally occurring genetic disorder of osteogenesis that is associated with overexpression of a bone morphogenetic protein.
  • —Adam B. Shafritz et al.New England Journal of Medicine22 Aug. 1996
called also stone man syndrome

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