Medical Dictionary

fibrodysplasia ossificans progressiva

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noun fi·bro·dys·pla·sia os·sif·i·cans pro·gres·si·va \ˌfī-brō-di-ˈsplā-zh(ē-)ə-ä-ˈsi-fə-ˌkanz-prə-ˈgre-sə-və\

Medical Definition of fibrodysplasia ossificans progressiva

  1. :  a rare hereditary disorder that is characterized by the progressive ossification of muscle and connective tissue and that is inherited as an autosomal recessive trait Fibrodysplasia ossificans progressiva in humans appears to be the only known example of a naturally occurring genetic disorder of osteogenesis that is associated with overexpression of a bone morphogenetic protein.—Adam B. Shafritz et al., New England Journal of Medicine, 22 Aug. 1996—called also stone man syndrome


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