factor V Leiden

noun
factor V Lei·​den | \-ˈlī-dᵊn \

Medical Definition of factor V Leiden 

1 : a point mutation producing an abnormal version of factor V that is resistant to inactivation and causes prolonged clotting of blood

2 also factor V Leiden thrombophilia : a genetic disorder caused by factor V Leiden that is marked by an increased risk of abnormal blood clot formation leading especially to deep vein thrombosis or pulmonary embolism

Note: Factor V Leiden is inherited as an autosomal dominant trait requiring that only one parent pass on a copy of the defective gene on a chromosome other than a sex chromosome. When both parents carry the defective gene, factor V Leiden is inherited as a recessive, more serious condition.

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Dictionary Entries near factor V Leiden

factor V

factor VII

factor VIII

factor V Leiden

factor X

factor XI

factor XII

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