Medical Definition of cranial fossa
: any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity:a: the posterior one that is the largest and deepest of the three and lodges the cerebellum, pons, and medulla oblongata—called also posterior cranial fossa, posterior fossab: the middle one that lodges the temporal lobes laterally and the hypothalamus medially—called also middle cranial fossa, middle fossac: the anterior one that lodges the frontal lobes—called also anterior cranial fossa, anterior fossa
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