contraindication

noun

con·​tra·​in·​di·​ca·​tion ˌkän-trə-ˌin-də-ˈkā-shən How to pronounce contraindication (audio)
: something (such as a symptom or condition) that makes a particular treatment or procedure inadvisable

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For doctors, an indication is a symptom or circumstance that makes a particular medical treatment desirable. Serious anxiety, for example, is often an indication for prescribing a tranquilizer. A contraindication, then, is a symptom or condition that makes a treatment risky, such as taking certain other medications at the same time. Drugs and conditions that are contraindicated for a medication are listed on its label, and reeled off at high speed in TV ads. Patients can guard against the dangers of drug interaction by reading labels carefully and making sure their doctors know what else they're currently taking.

Examples of contraindication in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
For a full list of safety considerations and contraindications, visit Pfizer's official Paxlovid safety page. Amanda Castro, MSNBC Newsweek, 19 Aug. 2025 These therapies require careful screening, have contraindications, and aren’t appropriate for all patients. Andre Mouchard, Oc Register, 18 Aug. 2025 This evolution will steadily progress to passive monitoring, for instance, checking prescription drug dosages, identifying potential interactions and flagging contraindications. London Business School, Forbes.com, 6 June 2025 Nearly three of every five people with ESRD have a contraindication for a kidney transplant.30 The two main types of dialysis are:31 Hemodialysis uses a special machine that mechanically removes, filters, and returns your blood to active circulation. Robert Burakoff, Verywell Health, 26 Feb. 2025 See All Example Sentences for contraindication

Word History

First Known Use

1623, in the meaning defined above

Time Traveler
The first known use of contraindication was in 1623

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Cite this Entry

“Contraindication.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/contraindication. Accessed 7 Sep. 2025.

Medical Definition

contraindication

noun
con·​tra·​in·​di·​ca·​tion -ˌin-də-ˈkā-shən How to pronounce contraindication (audio)
: something (as a symptom or condition) that makes a particular treatment or procedure inadvisable
Last Updated: - Updated example sentences
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