medical Definition of cleidocranial dysplasia
:a rare congenital condition characterized especially by partial or complete absence of the clavicles, defective ossification of the skull, and faulty occlusion due to missing, misplaced, or extra teeth
- Characteristics of cleidocranial dysplasia are alveolar bone abnormalities, impaired dental exfoliation, supernumerary teeth, and lack of cementum in roots.
- —Bodo Grimbacher et al., The New England Journal of Medicine, 4 Mar. 1999
Note:
Cleidocranial dysplasia is typically inherited as an autosomal dominant trait requiring that one parent pass on a copy of the defective gene on a chromosome other than a sex chromosome.
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